Monografías Plus      Agregar a favoritos      Ayuda      Português      Ingles     
 Página anterior Volver al principio del trabajoPágina siguiente 

Desarrollo embrionario del pelo (página 5)

Partes: 1, 2, 3, 4, 5

60. Lorenzo EM. Familial study of hirsutism. J Clin Endocrinol

1970 31:556-564

61. Mahoudeau JA, Bardin CW, Lipsett MB. The metabolic

clearance rate and origin of plasma dihydrotestosterone in

man and its conversion to the 5a-androstenediols. J Clin

Invest 1971 50:1338-1344

62. Marugo M, Bernasconi D, Meozzi M, Del Monte P, Zino V,

Primarolo P, Badaracco B. The use of flutamide in the

management of hirsutism. J Endocrinol Invest 1994 17:195-199

Revista de Endocrinología Ginecológica y Reproductiva 17

63. Mathur RS, Moody LO, Landgrebe S, Williamson HO. Plasma

a n d rogens and sex hormone binding globulin in the

evaluation of hirsute females. Fertil Steril 1981 35:29-35

64. Mauvais-Jarvis P. Regulation of androgen receptor and 5-

reductase in the skin of normal and hirsute women. Clin

Endocrinol Metab 1986 15:307-317

65. McKenna TJ, Miller RB, Liddle GW. Plasma pregnenolone

and 17-OH pregnenolone in patients with adrenal tumors,

ACTH excess, or idiopathic hirsutism. J Clin Endocrinol

Metab 1977 44:231-236

66. Mehta A, Matwijiw I, Taylor PJ, Salamon EA, Kredentser JV,

Faiman C. Should androgen levels be measured in hirsute

women with normal menstrual cycles? Int J Fertil 1992 37:354-357

67. Meikle AW, Odell WD. Effect of short and long-term

dexamethasone on 3a-androstanediol glucuronide in hirsute

women. Fertil Steril 1986 46:227-231

68. Mowszowicz I, Melanitou E, Doukani A, Wright F, Kuttenn F,

Mauvais-Jarvis P. Androgen binding capacity and 5areductase

activity in pubic skin fibroblasts from hirsute

patients. J Clin Endocrinol Metab 1983 56:1209-1213

69. Müderris II, Bayram F, Sahin Y, Kelestimur F, Tutus A, Ayata

D. The efficacy of 250 mg/day flutamide in the treatment of

patients with hirsutism. Fertil Steril 1996 66:220-222

70. O"Brien RC, Cooper ME, Murray RML, Seeman E, Thomas AK,

Jerums G. Comparison of sequential cypro t e rone acetate/

e s t rogen vs. spironolactone/oral contraceptive in the tre a t m e n t

of hirsutism. J Clin Endocrinol Metab 1991 72:1008-1013

71. Oh HS, Smart RC. An estrogen receptor pathway regulates

the telogen anagen hair follicle transition and influences

epidermal cell proliferation. Proc Natl Acad Sci USA 1996


72. Pang S, Wang M, Jeffries S, Riddick L, Clark A, Estrada E.

Normal and elevated 3a-androstanediol glucuro n i d e

concentrations in women with various causes of hirsutism

and its correlation with degree of hirsutism and androgen

levels. J Clin Endocrinol Metab 1992 75:243-48

73. Paoletti A, Cagnacci A, Orru M, Ajossa S, Guerriero S, Melis

G. Treatment with flutamide improves hyperinsulinemia in

women with idiopathic hirsutism. Fertil Steril 1999 72(3):448-453

74. Paoletti AM, Cagnacci A, Orru M, Ajossa S, Guerriero S, Melis

GB. Treatment with flutamide improves hyperinsulinemia in

women with idiopathic hirsutism. Fertil Steril 1999 72:448-453

75. Paulson RJ, Serafini PC, Catalino JA, Lobo RA. Measurements

of 3a, 17 b-androstanediol glucuronide in serum and urine

and the correlation with skin 5a-reductase activity. Fertil

Steril 1996 46:222-226

76. Philpott MP, Sanders DA, Kealey T. Effects of insulin and

insulin-like growth factors on cultured human hair follicles:

IGF-1 at physiologic concentrations is an important regulator of

hair follicle growth in vitro. J Invest Dermatol 1994 102:857-861

77. Pittaway DE, Maxson WS, Wentz AC. Spironolactone in

combination drug therapy for unresponsive hirsutism. Fertil

Steril 1985 43: 878-882

78. Pugeat M, Forest M, Nisula B, Corniau, De Pere t t i ,

Tourniaire. Evidence of excessive androgen secretion by

both the ovary and the adrenal in patients with idiopathic

hirsutism. Obstet Gynecol 1982 59:46-51

79. Randall VA. Androgens and human hair growth. Clin

Endocrinol 1994 (Oxf) 40:439-457

80. Rittmaster RS, Thompson DL. Effect of leuprolide and

dexamethasone on hair growth and hormone levels in

hirsute women: the relative importance of the ovary and the

adrenal in the pathogenesis of hirsutism. J Clin Endocrinol

Metab 1990 70:1096-1102

81. Rittmaster RS. Androgen conjugates: physiology and clinical

significance. Endocr Rev 1993 14:121-132

82. Rittmaster RS. Finasteride. N Engl J Med 1994 330:120-125

83. San Millan JL, Sancho J, Calvo RM. Role of pentanucleotide

(TTTTA) polymorphism in the promoter of the CYP11 gene

in the pathogenesis of hirsutism. Fertil Steril 2001 75(4):797-802

84. Sawaya ME, Price VH. Different levels of 5 a-reductase type

I and II, aromatase, and androgen receptor in hair follicles

of women and men with androgenetic alopecia. J Invest

Dermatol 1997 109:296-300

85. Sawaya ME, Shalita AR. Androgen receptor polymorphisms

(CAG repeat lengths) in androgenetic alopecia, hirsutism

and acne. J Cutan Med Surg 1998 3:9-15

86. Serafini P, Lobo RA. Increased 5a-reductase activity in

idiopathic hirsutism. Fertil Steril 1985 43:74-78

87. Serafini P, Lobo RA. The effects of spironolactone on adre n a l

s t e roidogenesis in hirsute women. Fertil Steril 1985 44:595-599

88. Stenn, Paus, Filippi. Letter to the Editor. J Invest Dermatol

1998 110:95

8 9 . Tartagni M, Schonauer L, De Salvia M, Cicinelli E, De

P e rgola G, D"Addario V. Comparison of Diane 35 and

Diane 35 plus finasteride in the treatment of hirsutism 2000

7 3 ( 4 ) : 7 1 8 - 7 2 3

90. Thigpen AE, Silver RI, Guilleyard JM, Casey ML, McConnell

JD, Russell DW. Tissue distribution and ontogeny of steroid

5-reductase isoenzyme expression. J Clin Invest 1993 92:903-


91. Thomas JP, Oake RJ. Androgen metabolism in the skin of

hirsute women. J Clin Endocrinol Metab 1974 38:19-22

92. Tolino A, Petrone A, Sarnacchiaro F, Cirillo D, Ronsini S,

Lombardi G, Nappi C. Finasteride in the treatment of

hirsutism: new therapeutic perspectives. Fertil Steril 1996 66:61-65

93. Venturoli S, Marescalchi O, Colombo FM, Macrelli S, Ravaioli

B, Bagnoli A, Paradisi R, Flamigni C. A pro s p e c t i v e

randomized trial comparing low dose flutamide, finasteride,

ketoconazole, and cyproterone acetate-estrogen regimens in the treatment of hirsutism. J Clin Endocrinol Metab 1999 84:1304-1310

94. Vermeulen A, Stoica T, Verdonck L. The apparent free testosterone concentration, an index of androgenicity. J Clin

Endocrinol 1971 33:759-767

95. Vottero A, Stratakis C, Ghizzoni L, Longui C, Karl M, Chrousos G. Androgen Receptor-Mediated Hypersensitivity

to Androgens in Women with Nonhyperandro g e n i c

Hirsutism: Skewing of X-Chromosome Inactivation. J Clin Endocrinol Metab 1999 84(3):1091-1095

96. Wahe M, Antonipillai I, Horton R. Effects of transforming growth factor band epidermal growth factor on steroid 5areductase activity in genital skin fibroblasts. Mol Cell Endocrinol 1993 98: 55-59 97. Wilson J 1996 Androgens. In: Gilman AG, Rall TW, Nies AS, Taylor P (ed) Goodman and Gilman"s The Pharmacological Basis of Therapeutics, ed 9. McGraw Hill Publishers, New York, pp 1441-1457

98. Wudy S, Wachter U, Homoki J, Teller W. 5 alpha-androstane- 3 alpha, 17 beta-diol and 5 alpha-andostane-3 alpha, 17 beta-diol-glucuronede in plasma of anormal children, adults and patients with idiopathic hirsutism: a mass spectrometric study. Eur J Endocrinol 1996 134(1):87-92

99. Young RL, Goldzieher JW, Elkind-Hirsch K. The endocrine effects of spironolactone used as an antiandrogen. Fertil

Steril 1987 48: 223-228



Figura 1. Desarrollo del pelo


Figura 2. Formación total del folículo piloso y formación del pelo



Figura 3. Niño con Alopecia


Figura 4. Niña con Hipertricosis


Figura 6. Alteración del folículo piloso: Tricoepitelioma múltiple (epitelioma adenoide quístico)


Figura 7. Alopecia andrógena: Fases de calvice.







Villegas Huam?n, Yenner Antonio



Dr. ?lvarez Carrillo Javier Dr. Cruzalegui Henr?quez Rodil Dr. Flori?n Zavaleta Luis Dr. Fonseca Guillermo

?REA: Embriolog?a M?dica





FECHA: 21/07/08

Partes: 1, 2, 3, 4, 5

 Página anterior Volver al principio del trabajoPágina siguiente 


Trabajos relacionados

Ver mas trabajos de Biologia


Nota al lector: es posible que esta página no contenga todos los componentes del trabajo original (pies de página, avanzadas formulas matemáticas, esquemas o tablas complejas, etc.). Recuerde que para ver el trabajo en su versión original completa, puede descargarlo desde el menú superior.

Todos los documentos disponibles en este sitio expresan los puntos de vista de sus respectivos autores y no de El objetivo de es poner el conocimiento a disposición de toda su comunidad. Queda bajo la responsabilidad de cada lector el eventual uso que se le de a esta información. Asimismo, es obligatoria la cita del autor del contenido y de como fuentes de información.